A New Family of Vinyl Selenocyanates with the Amide Function Based on the Reaction of Potassium Selenocyanate with 3-Trimethylsilyl-2-Propynamides

An efficient approach to a novel family of (Z)-3-amino-3-oxo-1-propenyl selenocyanates was developed based on the reaction KSeCN with 3-trimethylsilyl-2-propynamides in presence ammonium chloride methanol. The accompanied by desilylation process. products were not formed under same conditions absence chloride, which used for first time reactions acetylenes. use this new methodology allowed carry out regio- and stereoselective fashion as anti-addition affording vinyl (Z)-configuration high yields.